diff --git a/meta/classes-recipe/rust-target-config.bbclass b/meta/classes-recipe/rust-target-config.bbclass
index 334f2e7d5f..f7aa6c74d8 100644
--- a/meta/classes-recipe/rust-target-config.bbclass
+++ b/meta/classes-recipe/rust-target-config.bbclass
@@ -153,7 +153,7 @@ TARGET_C_INT_WIDTH[aarch64] = "32"
 MAX_ATOMIC_WIDTH[aarch64] = "128"
 
 ## x86_64-unknown-linux-{gnu, musl}
-DATA_LAYOUT[x86_64] = "e-m:e-i64:64-f80:128-n8:16:32:64-S128"
+DATA_LAYOUT[x86_64] = "e-m:e-p270:32:32-p271:32:32-p272:64:64-i64:64-i128:128-f80:128-n8:16:32:64-S128"
 TARGET_ENDIAN[x86_64] = "little"
 TARGET_POINTER_WIDTH[x86_64] = "64"
 TARGET_C_INT_WIDTH[x86_64] = "32"
diff --git a/meta/lib/oeqa/selftest/cases/rust.py b/meta/lib/oeqa/selftest/cases/rust.py
index cbe6366f75..88d7bb9518 100644
--- a/meta/lib/oeqa/selftest/cases/rust.py
+++ b/meta/lib/oeqa/selftest/cases/rust.py
@@ -83,7 +83,6 @@ class RustSelfTestSystemEmulated(OESelftestTestCase, OEPTestResultTestCase):
                             'src/tools/tidy/src/',
                             'tests/assembly/asm/aarch64-outline-atomics.rs',
                             'tests/codegen/abi-main-signature-32bit-c-int.rs',
-                            'tests/codegen/i128-x86-align.rs',
                             'tests/codegen/issues/issue-122805.rs',
                             'tests/codegen/thread-local.rs',
                             'tests/mir-opt/',